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1

Real-time shape approximation and fingerprinting of single proteins using a nanopore

Yusko, Erik C., Bruhn, Brandon R., Eggenberger, Olivia M., Houghtaling, Jared, Rollings, Ryan C., Walsh, Nathan C., Nandivada, Santoshi, Pindrus, Mariya, Hall, Adam R., Sept, David, Li, Jiali, Kalonia

Journal:

Nature Nanotechnology

Year:

2016

Language:

english

File:

PDF, 4.26 MB

english, 2016

2

Controlling protein translocation through nanopores with bio-inspired fluid walls

Yusko, Erik C., Johnson, Jay M., Majd, Sheereen, Prangkio, Panchika, Rollings, Ryan C., Li, Jiali, Yang, Jerry, Mayer, Michael

Journal:

Nature Nanotechnology

Year:

2011

Language:

english

File:

PDF, 3.88 MB

english, 2011

3

Gramicidin Pores Report the Activity of Membrane-Active Enzymes

Majd, Sheereen, Yusko, Erik C., MacBriar, Alexander D., Yang, Jerry, Mayer, Michael

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 61 KB

english, 2010

4

Gramicidin Pores Report the Activity of Membrane-Active Enzymes

Majd, Sheereen, Yusko, Erik C., MacBriar, Alexander D., Yang, Jerry, Mayer, Michael

Journal:

Journal of the American Chemical Society

Year:

2009

Language:

english

File:

PDF, 2.30 MB

english, 2009

5

Fractionated radiation therapy stimulates anti-tumor immunity mediated by both resident and infiltrating polyclonal T-cell populations when combined with PD1 blockade

Dovedi, Simon J, Cheadle, Eleanor J, Popple, Amy, Poon, Edmund, Morrow, Michelle, Stewart, Ross, Yusko, Erik, Sanders, Catherine, Vignali, Marissa, Emerson, Ryan, Robins, Harlan, Wilkinson, Robert W,

Journal:

Clinical Cancer Research

Year:

2017

Language:

english

File:

PDF, 5.00 MB

english, 2017

6

Applications of biological pores in nanomedicine, sensing, and nanoelectronics

Sheereen Majd, Erik C Yusko, Yazan N Billeh, Michael X Macrae, Jerry Yang, Michael Mayer

Journal:

Current Opinion in Biotechnology

Year:

2010

Language:

english

File:

PDF, 1.99 MB

english, 2010

7

Ultrafast laser fabrication of submicrometer pores in borosilicate glass

An, Ran, Uram, Jeffrey D., Yusko, Erik C., Ke, Kevin, Mayer, Michael, Hunt, Alan J.

Journal:

Year:

2008

Language:

english

File:

PDF, 259 KB

english, 2008

8

Nanopores with Fluid Walls

Yusko, Erik C., Johnson, Jay M., Majd, Sheereen, Prangkio, Panchika, Rollings, Ryan C., Li, Jiali, Yang, Jerry, Mayer, Michael

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 33 KB

english, 2011

9

Electroosmotic Flow Can Generate Ion Current Rectification in Nano- and Micropores

Yusko, Erik C., An, Ran, Mayer, Michael

Journal:

Year:

2010

Language:

english

File:

PDF, 1.72 MB

english, 2010

10

A Model for the Interfacial Kinetics of Phospholipase D Activity on Long-Chain Lipids

Majd, Sheereen, Yusko, Erik C., Yang, Jerry, Sept, David, Mayer, Michael

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 736 KB

english, 2013

11

Mechanical Characterization of the Yeast Centrosome

Yusko, Erik C., Graczyk, Beth, Fong, Kim, Davis, Trisha, Asbury, Charles

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 40 KB

english, 2014

12

Lipid Bilayers in Nanopores to Vary their Diameter, Characterize Amyloid-β Aggregates and Monitor the Activity of Membrane-Active Enzymes

Yusko, Erik C., Johnson, Jay, Billeh, Yazan, Majd, Sheereen, Rollings, Ryan, Li, Jiali, Yang, Jerry, Mayer, Michael

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 36 KB

english, 2010

13

Nanopores with Fluid Walls for Determining the Shape, Dipole Moment, and Rotational Diffusion Coefficient of Non-Spherical Proteins

Yusko, Erik C., Bruhn, Brandon R., Rollings, Ryan C., Li, Jiali, Sept, David, Mayer, Michael

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 56 KB

english, 2013

14

Fluidic Diodes in Nano- and Microscale Pores to Detect Drug Aggregation

Yusko, Erik C., An, Ran, Mayer, Michael

Journal:

Biophysical Journal

Year:

2009

Language:

english

File:

PDF, 36 KB

english, 2009

15

Developing Nanopores with Fluid Walls for Improved, Single-Molecule Biosensors

Yusko, Erik C., Petti, Alex M., Prangkio, Panchika, Rollings, Ryan C., Li, Jiali, Yang, Jerry, Mayer, Michael

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 100 KB

english, 2012

16

Characterizing Shape, Dipole Moment, and Rotation of Single Proteins in Nanopores

Bruhn, Brandon R., Yusko, Erik C., Eggenberger, Olivia, Rollings, Ryan C., Walsh, Nathan C., Pindrus, Mariya, Sept, David, Li, Jiali, Kalonia, Devendra S., Mayer, Michael

Journal:

Biophysical Journal

Year:

2014

Language:

english

File:

PDF, 128 KB

english, 2014

17

Single-Particle Characterization of Aβ Oligomers in Solution

Yusko, Erik C., Prangkio, Panchika, Sept, David, Rollings, Ryan C., Li, Jiali, Mayer, Michael

Journal:

Year:

2012

Language:

english

File:

PDF, 3.19 MB

english, 2012

18

Current oscillations generated by precipitate formation in the mixing zone between two solutions inside a nanopore

Yusko, Erik C, Billeh, Yazan N, Mayer, Michael

Journal:

Journal of Physics Condensed Matter

Year:

2010

Language:

english

File:

PDF, 785 KB

english, 2010

19

IMCT-11NEXT GENERATION T CELL RECEPTOR SEQUENCING CAN IDENTIFY, QUANTIFY, AND TRACK TUMOR-SPECIFIC T CELL POPULATIONS BEFORE AND AFTER DENDRITIC CELL VACCINATION IN GLIOBLASTOMA MULTIFORME PATIENTS

Sedighim, Shaina, Hsu, Melody, Antonios, Joseph, Emerson, Ryan, Yusko, Erik, Sanders, Catherine, Davidson, Tom, Liau, Linda, Prins, Robert

Journal:

Year:

2015

Language:

english

File:

PDF, 27 KB

english, 2015

20

Single Molecule Characterization of Cholera Toxin and its Interaction with Gm1 Gangliosides Using Lipid-Coated Nanopores

Vinnakota, Anirudh, Bruhn, Brandon R., Yusko, Erik C., Mayer, Michael

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 43 KB

english, 2015

21

Ibrutinib Therapy Increases T Cell Repertoire Diversity in Patients with Chronic Lymphocytic Leukemia

Yin, Qingsong, Sivina, Mariela, Robins, Harlan, Yusko, Erik, Vignali, Marissa, O’Brien, Susan, Keating, Michael J., Ferrajoli, Alessandra, Estrov, Zeev, Jain, Nitin, Wierda, William G., Burger, Jan A.

Journal:

The Journal of Immunology

Year:

2017

Language:

english

File:

PDF, 1.47 MB

english, 2017

22

Direct measurement of microtubule attachment strength to yeast centrosomes

Fong, Kimberly K., Sarangapani, Krishna K., Yusko, Erik C., Riffle, Michael, Llauró, Aida, Graczyk, Beth, Davis, Trisha N., Asbury, Charles L., Bloom, Kerry

Journal:

Molecular Biology of the Cell

Year:

2017

Language:

english

File:

PDF, 1.30 MB

english, 2017

23

TCR Repertoire Intratumor Heterogeneity in Localized Lung Adenocarcinomas: an Association with Predicted Neoantigen Heterogeneity and Postsurgical Recurrence

Reuben, Alexandre, Gittelman, Rachel M., Gao, Jianjun, Zhang, Jiexin, Yusko, Erik, Wu, Chang-Jiun, Emerson, Ryan, Zhang, Jianhua, Tipton, Christopher M, Li, Jun, Quek, Kelly, Gopalakrishnan, Vancheswa

Journal:

Cancer Discovery

Year:

2017

Language:

english

File:

PDF, 1.09 MB

english, 2017

24

Concurrent PD-1 Blockade Negates the Effects of OX40 Agonist Antibody in Combination Immunotherapy through Inducing T-cell Apoptosis

Shrimali, Rajeev K., Ahmad, Shamim, Verma, Vivek, Zeng, Peng, Ananth, Sudha, Gaur, Pankaj, Gittelman, Rachel M., Yusko, Erik, Sanders, Catherine, Robins, Harlan, Hammond, Scott A., Janik, John E., Mkr

Journal:

Cancer Immunology Research

Year:

2017

Language:

english

File:

PDF, 1.84 MB

english, 2017

25

Immune correlates in a Phase II clinical trial with ipilimumab in combination with finite androgen deprivation therapy in patients with metastatic non-castrate prostate cancer

Subudhi, Sumit K, Aparicio, Ana, Gao, Jianjun, Zurita, Amado, John, Araujo, Logothetis, Christopher, Rao, Brinda, Vence, Luis, Allison, James, Emerson, Ryan O, Yusko, Erik, Vignali, Marissa, Robins, H

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2015

Language:

english

File:

PDF, 210 KB

english, 2015

26

Contribution of systemic and somatic factors to clinical response and resistance to PD-L1 blockade in urothelial cancer: An exploratory multi-omic analysis

Snyder, Alexandra, Nathanson, Tavi, Funt, Samuel A., Ahuja, Arun, Buros Novik, Jacqueline, Hellmann, Matthew D., Chang, Eliza, Aksoy, Bulent Arman, Al-Ahmadie, Hikmat, Yusko, Erik, Vignali, Marissa, B

Journal:

Year:

2017

Language:

english

File:

PDF, 3.30 MB

english, 2017

27

Multivariate Analyses of Amyloid-Beta Oligomer Populations Indicate a Connection between Pore Formation and Cytotoxicity

Prangkio, Panchika, Yusko, Erik C., Sept, David, Yang, Jerry, Mayer, Michael, Zheng, Jie

Journal:

Year:

2012

Language:

english

File:

PDF, 1.10 MB

english, 2012

28

Alloreactive T Cell Receptor Diversity against Structurally Similar or Dissimilar HLA-DP Antigens Assessed by Deep Sequencing

Arrieta-Bolaños, Esteban, Crivello, Pietro, Metzing, Maximilian, Meurer, Thuja, Ahci, Müberra, Rytlewski, Julie, Vignali, Marissa, Yusko, Erik, van Balen, Peter, Horn, Peter A., Falkenburg, J. H. Fred

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 6.63 MB

english, 2018

29

Neoadjuvant ipilimumab (3 mg/kg or 10 mg/kg) and high dose IFN-α2b in locally/regionally advanced melanoma: safety, efficacy and impact on T-cell repertoire

Tarhini, Ahmad, Lin, Yan, Lin, Huang, Rahman, Zahra, Vallabhaneni, Priyanka, Mendiratta, Prateek, Pingpank, James F., Holtzman, Matthew P., Yusko, Erik C., Rytlewski, Julie A., Rao, Uma N. M., Ferris,

Journal:

Journal for ImmunoTherapy of Cancer

Year:

2018

Language:

english

File:

PDF, 1006 KB

english, 2018

30

The effect of anti-CTLA4 treatment on peripheral and intra-tumoral T cells in patients with hepatocellular carcinoma

Agdashian, David, ElGindi, Mei, Xie, Changqing, Sandhu, Milan, Pratt, Drew, Kleiner, David E., Figg, William D., Rytlewski, Julie A., Sanders, Catherine, Yusko, Erik C., Wood, Bradford, Venzon, David,

Journal:

Cancer Immunology, Immunotherapy

Year:

2019

Language:

english

File:

PDF, 1.67 MB

english, 2019

31

Model to improve specificity for identification of clinically-relevant expanded T cells in peripheral blood

Rytlewski, Julie, Deng, Shibing, Xie, Tao, Davis, Craig, Robins, Harlan, Yusko, Erik, Bienkowska, Jadwiga, Beavis, Paul A.

Journal:

Year:

2019

File:

PDF, 1.48 MB

2019

32

The impact of CTLA-4 blockade and interferon-α on clonality of T-cell repertoire in the tumor microenvironment and peripheral blood of metastatic melanoma patients

Khunger, Arjun, Rytlewski, Julie A., Fields, Paul, Yusko, Erik C., Tarhini, Ahmad A.

Journal:

Year:

2019

Language:

english

File:

PDF, 2.84 MB

english, 2019

33

T Cell Repertoire Dynamics during Pregnancy in Multiple Sclerosis

Ramien, Caren, Yusko, Erik C., Engler, Jan Broder, Gamradt, Stefanie, Patas, Kostas, Schweingruber, Nils, Willing, Anne, Rosenkranz, Sina Cathérine, Diemert, Anke, Harrison, Anja, Vignali, Marissa, Sa

Journal:

Year:

2019

Language:

english

File:

PDF, 1.88 MB

english, 2019

34

T Cell Clonal Dynamics Determined by High-Resolution TCR-Î² Sequencing in Recipients after Allogeneic Hematopoietic Cell Transplantation

Leick, Mark, Gittelman, Rachel M., Yusko, Erik, Sanders, Catherine, Robins, Harlan, DeFilipp, Zachariah, Nikiforow, Sarah, Ritz, Jerome, Chen, Yi-Bin

Journal:

Biology of Blood and Marrow Transplantation

Year:

2020

File:

PDF, 1.55 MB

2020